가와사끼병 후에 발생한 관상동맥 질환에 대한 시술 또는 수술적 치료의 결과
Results of Catheter or Surgical Intervention for Coronary Artery Disease after Kawasaki Disease
Abstract
Background: Coronary artery disease is serious complication of Kawasaki disease (KD). Percutaneous coronary intervention and coronary artery bypass grafting (CABG) are reported with limited data on indications and efficacy. Objectives: To report follow-up results of catheter or surgical intervention for coronary artery disease after KD in a single center Methods: We retrospectively reviewed on medical records of patients who underwent coronary angiography after KD in Sejong General Hospital from January 1994 to March 2017. Results: Coronary angiography was performed in 49 patients at the median age of 3.9 years (range, 8 months to 17 years) and the median time interval from diagnosis of KD was 11 months. Coronary angiography showed coronary aneurysm with/without stenosis in 36 patients. Among them, catheter intervention was performed in 6 patients (aged 13 months to 9 years) and CABG was performed in 3 patients at the age of 6, 12, and 14 years, respectively. Percutaneous transluminal coronary-balloon angioplasty ( PTCA) was performed in all 6 patients, stent implantation in 3, and percutaneous transluminal coronary rotational ablation in 2. During the 16.1 ± 6.0 years of follow up, total obstruction of coronary artery was observed in 3 patients and significant stenosis in 2 even after the catheter intervention. None of the patients needed reintervention after CABG. In patients who did not underwent catheter or surgical intervention, 3 patients showed complete regression of coronary aneurysm during follow-up and 5 experienced total occlusion of right coronary artery without myocardial infarction due to multiple collateral arteries form left coronary artery. Conclusions: Catheter intervention for Kawasaki disease can be accomplished, but the long-term efficacy is questionable. In multi-vessel coronary disease, surgical revascularization can be performed effectively. Close sequential follow-up evaluation is important in the patients with coronary artery disease after KD.