가와사끼병 후에 발생한 관상동맥 질환에 대한 시술 또는 수술적 치료의 결과

가와사끼병 후에 발생한 관상동맥 질환에 대한 시술 또는 수술적 치료의 결과

Results of Catheter or Surgical Intervention for Coronary Artery Disease after Kawasaki Disease

(구연):
Release Date : 2017. 10. 27(금)
Hye Won Kwon1, Seong Ho Kim1, Sang-Yun Lee1, So-Ick Jang 1, Rak Kyeong Choi2 , Chang Ha Lee 3
Sejong General Hospital Pediatrics1
Sejong General Hospital Internal medicine, division of Cardiology2
Sejong General Hospital Thoracic and cardiovascular surgery 3
권혜원1, 김성호1, 이상윤1, 장소익1, 최락경2 , 이창하3
세종병원 소아청소년과1
세종병원 심장 내과2
세종병원 흉부 외과 3

Abstract

Background: Coronary artery disease is serious complication of Kawasaki disease (KD). Percutaneous coronary intervention and coronary artery bypass grafting (CABG) are reported with limited data on indications and efficacy. Objectives: To report follow-up results of catheter or surgical intervention for coronary artery disease after KD in a single center Methods: We retrospectively reviewed on medical records of patients who underwent coronary angiography after KD in Sejong General Hospital from January 1994 to March 2017. Results: Coronary angiography was performed in 49 patients at the median age of 3.9 years (range, 8 months to 17 years) and the median time interval from diagnosis of KD was 11 months. Coronary angiography showed coronary aneurysm with/without stenosis in 36 patients. Among them, catheter intervention was performed in 6 patients (aged 13 months to 9 years) and CABG was performed in 3 patients at the age of 6, 12, and 14 years, respectively. Percutaneous transluminal coronary-balloon angioplasty ( PTCA) was performed in all 6 patients, stent implantation in 3, and percutaneous transluminal coronary rotational ablation in 2. During the 16.1 ± 6.0 years of follow up, total obstruction of coronary artery was observed in 3 patients and significant stenosis in 2 even after the catheter intervention. None of the patients needed reintervention after CABG. In patients who did not underwent catheter or surgical intervention, 3 patients showed complete regression of coronary aneurysm during follow-up and 5 experienced total occlusion of right coronary artery without myocardial infarction due to multiple collateral arteries form left coronary artery. Conclusions: Catheter intervention for Kawasaki disease can be accomplished, but the long-term efficacy is questionable. In multi-vessel coronary disease, surgical revascularization can be performed effectively. Close sequential follow-up evaluation is important in the patients with coronary artery disease after KD.

Keywords: Kawasaki disease , Coronary artery disease , Coronary intervention and surgery